Bioscreen C system provides a platform for these measurements to be made. The organism of interest and any growth medium may be selected. Specimens are manually dispensed using a 5 or 10 channel pipette into the wells of a special microplate.

Honeycomb Microplate:

This 10 by 10 well plate (400µl per well) is designed to provide uniform temperature across each of the 100 wells in the plate. A fitted plate lid with special characteristics eliminates troublesome condensation which can interfere with OD readings. (Biotek has many similiar Readers, please inquire!)

Bioscreen C Analyzer:

The instrument includes an incubator to provide constant temperature and a linear shaker to assure good mixing. The instrument is equipped with a sensitive reader that measures turbidity, a technique more sensitive than a spectrophotometer. With 8 filters installed to measure specific wavelengths. Two 100 well sterile honeycomb plates with covers are handled by the instrument at one time, making it possible to run 200 samples simultaneously. Turbidometric measurements are made kinetically during the course of the run. This information is processed to generate microbiological growth curves, plotting turbidity vs. time and exported to a PC for report generation via Excel. The test length is from a single measurement to three months. Bioscreen C is extremely versatile - any microorganism (aerobic or anaerobic) can be grown with any liquid growth medium and with any chemical by using user-created test protocol.

Unrivaled Throughput:

Bioscreen C performs up to 200 microbiological experiments (each well is one test) simultaneously. By using Bioscreen C, one is able to complete as many tests in just a few weeks as would normally take a year by using traditional manual techniques. Bioscreen C work covers all main areas of microbiology, food microbiology, pharmaceutical/medical microbiology, environmental microbiology and university research microbiology.

Applications:

The range of tests is virtually endless - miniaturized bioassay (of vitamins, antibiotics, amino acids, etc.), effect of chemicals on pure and mixed cultures, development of antibiotics, QC of food (total count - CFU/g) and others. With Bioscreen C, one can monitor the growth of pure or mixed cultures and check the effect of single or multiple parameters (e.g. pH, temperature, chemicals) of different microorganisms.

Some examples of the thousands of tests that can be performed by Bioscreen C: toxicity measurement, stimulant and inhibitor screening, growth media development (wide range or selective), testing and rapid development of pharmaceutical, optimization of fermentation process and microbiological production, optimization of wastewater treatment process (sludge or biofilm) and single-cell-protein (SCP) production, development of preservative and antifungal, development of milk substitute, mutagenicity research, research microbiology, bacteriophage study, measurement of antimicrobial effect, water activity study, development of biosensor, in vitro testing, viability tests, ammonification, nitrification and denitrification studies, waste detoxification, phenol and heavy metal removal studies, bacteria measurement, theoretical study of metabolic processes (mathematical modeling), and many others.

Key Features:

• Kinetic measurement of turbidity of up to 200 samples simultaneously.
• Open system for almost any bacteria, fungi, yeast, cell or phage.
• Is an automation tool for all research microbiologists and for many clinical/industrial users.
• Linear shaking, incubating, OD measurement and reporting.
• Incubation temperature range is 1.0-60.0 °C in steps of 0.1 °C.
• Result Modes: 1) Color Growth Curves, 2) Assay Test Calculated Results, 3) OD Matrix.
• Reduces a year of manual experimentation to just a few weeks.